Long-Term Survival of Pig-to-Rhesus Macaque Renal Xenografts is Dependent on CD4 T cell Depletion

The shortage of available organs remains the greatest barrier to expanding access to transplantation. Despite advances in genetic editing and immunosuppression, survival in experimental models of kidney xenotransplantation has generally been limited to <100 days. We found that pre-transplant sele...

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Detalhes bibliográficos
Publicado no:Am J Transplant
Main Authors: Kim, SC, Mathews, DV, Breeden, CP, Higginbotham, LB, Ladowski, J, Martens, G, Stephenson, A, Farris, AB, Strobert, EA, Jenkins, J, Walters, EM, Larsen, CP, Tector, M, Tector, AJ, Adams, AB
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6658347/
https://ncbi.nlm.nih.gov/pubmed/30821922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.15329
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