Xenoantigen Deletion and Chemical Immunosuppression Can Prolong Renal Xenograft Survival.

OBJECTIVE: Xenotransplantation using pig organs could end the donor organ shortage for transplantation, but humans have xenoreactive antibodies that cause early graft rejection. Genome editing can eliminate xenoantigens in donor pigs to minimize the impact of these xenoantibodies. Here we determine...

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Detalhes bibliográficos
Publicado no:Ann Surg
Main Authors: Adams, Andrew B, Kim, Steven C, Martens, Gregory R, Ladowski, Joseph M, Estrada, Jose L, Reyes, Luz M, Breeden, Cindy, Stephenson, Allison, Eckhoff, Devin E, Tector, Matt, Tector, A. Joseph
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6382078/
https://ncbi.nlm.nih.gov/pubmed/30048323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SLA.0000000000002977
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