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From the Broad Phase II Trial to Precision Oncology: A Perspective on the Origins of Basket and Umbrella Clinical Trial Designs in Cancer Drug Development
Oncologic phase II trials that evaluate the activity of new therapeutic agents have evolved dramatically over the past 50 years. The standard approach beginning in the late 1960’s focused on individual studies that evaluated new anticancer agents against a wide range of both solid and hematopoietic...
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| Publicado no: | Cancer J |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6658138/ https://ncbi.nlm.nih.gov/pubmed/31335388 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PPO.0000000000000386 |
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