Sulforaphane enriched transcriptome of lung mitochondrial energy metabolism and provided pulmonary injury protection via Nrf2 in mice

Nrf2 is essential to antioxidant response element (ARE)-mediated host defense. Sulforaphane (SFN) is a phytochemical antioxidant known to affect multiple cellular targets including Nrf2-ARE pathway in chemoprevention. However, the role of SFN in non-malignant airway disorders remain unclear. To test...

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Vydáno v:Toxicol Appl Pharmacol
Hlavní autoři: Cho, Hye-Youn, Miller-DeGraff, Laura, Blankenship-Paris, Terry, Wang, Xuting, Bell, Douglas A., Lih, Fred, Deterding, Leesa, Panduri, Vijayalakshmi, Morgan, Daniel L., Yamamoto, Masayuki, Reddy, Anita J., Talalay, Paul, Kleeberger, Steven R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6658087/
https://ncbi.nlm.nih.gov/pubmed/30529165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2018.12.004
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