Interleukin-1β promotes interleulin-6 expression via ERK1/2 signaling pathway in canine dermal fibroblasts

Interleukin-6 (IL-6) is a pleiotropic cytokine involved in the regulation of the immune response and inflammation. In this study, we investigated effect of the proinflammatory cytokine interleukin-1β (IL-1β) on IL-6 expression in canine dermal fibroblasts. IL-1β induced IL-6 mRNA expression and prot...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Kitanaka, Nanako, Nakano, Rei, Sugiura, Kanae, Kitanaka, Taku, Namba, Shinichi, Konno, Tadayoshi, Nakayama, Tomohiro, Sugiya, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6658082/
https://ncbi.nlm.nih.gov/pubmed/31344106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0220262
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