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ERK2 and JNK1 contribute to TNF-α-induced IL-8 expression in synovial fibroblasts

Tumor necrosis factor α (TNF-α) induces the expression and secretion of interleukin 8 (IL-8), which contributes to synovitis in rheumatoid arthritis (RA). To elucidate the mechanism of the onset of RA, we used synovial fibroblasts without autoimmune inflammatory diseases and investigated MAPK signal...

詳細記述

保存先:
書誌詳細
出版年:PLoS One
主要な著者: Namba, Shinichi, Nakano, Rei, Kitanaka, Taku, Kitanaka, Nanako, Nakayama, Tomohiro, Sugiya, Hiroshi
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5555573/
https://ncbi.nlm.nih.gov/pubmed/28806729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0182923
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