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ERK2 and JNK1 contribute to TNF-α-induced IL-8 expression in synovial fibroblasts
Tumor necrosis factor α (TNF-α) induces the expression and secretion of interleukin 8 (IL-8), which contributes to synovitis in rheumatoid arthritis (RA). To elucidate the mechanism of the onset of RA, we used synovial fibroblasts without autoimmune inflammatory diseases and investigated MAPK signal...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5555573/ https://ncbi.nlm.nih.gov/pubmed/28806729 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0182923 |
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