Hypertonic saline downregulates endothelial cell-derived VEGF expression and reduces blood-brain barrier permeability induced by cerebral ischaemia via the VEGFR2/eNOS pathway

The aim of the present study was to explore the possible mechanisms by which hypertonic saline (HS) effectively ameliorates cerebral oedema via the vascular endothelial growth factor receptor 2 (VEGFR2)-mediated endothelial nitric oxide synthase (eNOS) pathway of endothelial cells in rats. A middle...

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Vydáno v:Int J Mol Med
Hlavní autoři: Wang, Qiaosheng, Deng, Yiyu, Huang, Linqiang, Zeng, Wenxin, Chen, Shenglong, Lv, Bo, Jiang, Wenqiang, Han, Yongli, Ding, Hongguang, Wen, Miaoyun, Zeng, Hongke
Médium: Artigo
Jazyk:Inglês
Vydáno: D.A. Spandidos 2019
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6657973/
https://ncbi.nlm.nih.gov/pubmed/31524227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2019.4262
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