HMGB1 enhances mechanical stress-induced cardiomyocyte hypertrophy in vitro via the RAGE/ERK1/2 signaling pathway

Pressure overload-induced cardiac hypertrophy is associated with a complex spectrum of pathophysiological mechanisms, including the inflammation response. High mobility group box-1 (HMGB1), a pro-inflammatory cytokine, is not only increased in myocardium under pressure overload, but also exacerbates...

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Publicado no:Int J Mol Med
Main Authors: Zhang, Lei, Yang, Xue, Jiang, Guoliang, Yu, Ying, Wu, Jian, Su, Yangang, Sun, Aijun, Zou, Yunzeng, Jiang, Hong, Ge, Junbo
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2019
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6657962/
https://ncbi.nlm.nih.gov/pubmed/31524228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2019.4276
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