Attenuation of chronic antiviral T-cell responses through constitutive COX2-dependent prostanoid synthesis by lymph node fibroblasts

Lymphoid T-zone fibroblastic reticular cells (FRCs) actively promote T-cell trafficking, homeostasis, and expansion but can also attenuate excessive T-cell responses via inducible nitric oxide (NO) and constitutive prostanoid release. It remains unclear how these FRC-derived mediators dampen T-cell...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:PLoS Biol
Autors principals: Schaeuble, Karin, Cannelle, Hélène, Favre, Stéphanie, Huang, Hsin-Ying, Oberle, Susanne G., Speiser, Daniel E., Zehn, Dietmar, Luther, Sanjiv A.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2019
Matèries:
Short Reports
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6657915/
https://ncbi.nlm.nih.gov/pubmed/31306410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000072
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars