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The safety and efficacy of novel agents targeting factor XI and XII in early phase human trials.

Although anticoagulation without hemorrhage is a primary aim, this vision has remained as yet out of reach. Even despite the superior safety profile of the direct oral anticoagulants, hemorrhage remains a major risk of anticoagulation. Selective inhibition of the contact pathway of coagulation, spec...

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Detalhes bibliográficos
Publicado no:Semin Thromb Hemost
Main Authors: DeLoughery, Emma, Olson, Sven R., Puy, Cristina, McCarty, Owen JT, Shatzel, Joseph J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6657806/
https://ncbi.nlm.nih.gov/pubmed/31216587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0039-1692439
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