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The safety and efficacy of novel agents targeting factor XI and XII in early phase human trials.

Although anticoagulation without hemorrhage is a primary aim, this vision has remained as yet out of reach. Even despite the superior safety profile of the direct oral anticoagulants, hemorrhage remains a major risk of anticoagulation. Selective inhibition of the contact pathway of coagulation, spec...

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Dades bibliogràfiques
Publicat a:Semin Thromb Hemost
Autors principals: DeLoughery, Emma, Olson, Sven R., Puy, Cristina, McCarty, Owen JT, Shatzel, Joseph J.
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6657806/
https://ncbi.nlm.nih.gov/pubmed/31216587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0039-1692439
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