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The safety and efficacy of novel agents targeting factor XI and XII in early phase human trials.
Although anticoagulation without hemorrhage is a primary aim, this vision has remained as yet out of reach. Even despite the superior safety profile of the direct oral anticoagulants, hemorrhage remains a major risk of anticoagulation. Selective inhibition of the contact pathway of coagulation, spec...
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| Veröffentlicht in: | Semin Thromb Hemost |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6657806/ https://ncbi.nlm.nih.gov/pubmed/31216587 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0039-1692439 |
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