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Synthesis of an α-phosphono-α,α-difluoroacetamide analogue of the diphosphoinositol pentakisphosphate 5-InsP(7)

Diphosphoinositol phosphates (PP-InsPs) are an evolutionarily ancient group of signalling molecules that are essential to cellular and organismal homeostasis. As the detailed mechanisms of PP-InsP signalling begin to emerge, synthetic analogues of PP-InsPs containing stabilised mimics of the labile...

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Foilsithe in:Medchemcomm
Main Authors: Riley, Andrew M., Wang, Huanchen, Shears, Stephen B., Potter, Barry V. L.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Royal Society of Chemistry 2019
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6657673/
https://ncbi.nlm.nih.gov/pubmed/31391889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9md00163h
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