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Synthetic tools for studying the chemical biology of InsP(8)

To synthesise stabilised mimics of InsP(8), the most phosphorylated inositol phosphate signalling molecule in Nature, we replaced its two diphosphate (PP) groups with either phosphonoacetate (PA) or methylenebisphosphonate (PCP) groups. Utility of the PA and PCP analogues was verified by structural...

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Bibliografische gegevens
Gepubliceerd in:Chem Commun (Camb)
Hoofdauteurs: Riley, Andrew M., Wang, Huanchen, Shears, Stephen B., L. Potter, Barry V.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Royal Society of Chemistry 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4643724/
https://ncbi.nlm.nih.gov/pubmed/26153667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5cc05017k
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