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Synthetic tools for studying the chemical biology of InsP(8)
To synthesise stabilised mimics of InsP(8), the most phosphorylated inositol phosphate signalling molecule in Nature, we replaced its two diphosphate (PP) groups with either phosphonoacetate (PA) or methylenebisphosphonate (PCP) groups. Utility of the PA and PCP analogues was verified by structural...
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Publicado no: | Chem Commun (Camb) |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Royal Society of Chemistry
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4643724/ https://ncbi.nlm.nih.gov/pubmed/26153667 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5cc05017k |
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