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Structure-Function Analysis of the Phosphoesterase Component of the Nucleic Acid End-Healing Enzyme Runella slithyformis HD-Pnk

Runella slithyformis HD-Pnk is the prototype of a family of dual 5′ and 3′ nucleic acid end-healing enzymes that phosphorylate 5′-OH termini and dephosphorylate 2′,3′-cyclic-PO(4), 3′-PO(4), and 2′-PO(4) ends. HD-Pnk is composed of an N-terminal HD phosphohydrolase module and a C-terminal P-loop pol...

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Podrobná bibliografie
Vydáno v:J Bacteriol
Hlavní autoři: Munir, Annum, Shuman, Stewart
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6657592/
https://ncbi.nlm.nih.gov/pubmed/31160396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00292-19
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