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Structure-Function Analysis of the Phosphoesterase Component of the Nucleic Acid End-Healing Enzyme Runella slithyformis HD-Pnk

Runella slithyformis HD-Pnk is the prototype of a family of dual 5′ and 3′ nucleic acid end-healing enzymes that phosphorylate 5′-OH termini and dephosphorylate 2′,3′-cyclic-PO(4), 3′-PO(4), and 2′-PO(4) ends. HD-Pnk is composed of an N-terminal HD phosphohydrolase module and a C-terminal P-loop pol...

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Detalhes bibliográficos
Publicado no:J Bacteriol
Main Authors: Munir, Annum, Shuman, Stewart
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6657592/
https://ncbi.nlm.nih.gov/pubmed/31160396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00292-19
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