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Pro: Tolvaptan delays the progression of autosomal dominant polycystic kidney disease

No treatment until now has directly targeted the mechanisms responsible for the development and growth of cysts in autosomal dominant polycystic kidney disease (ADPKD). Strong rationale and preclinical studies using in vitro and in vivo models justified the launching of two large phase 3 clinical tr...

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Detalhes bibliográficos
Publicado no:Nephrol Dial Transplant
Autor principal: Torres, Vicente E
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6657439/
https://ncbi.nlm.nih.gov/pubmed/30312438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ndt/gfy297
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