Tolvaptan in Patients with Autosomal Dominant Polycystic Kidney Disease

BACKGROUND: The course of autosomal dominant polycystic kidney disease (ADPKD) is often associated with pain, hypertension, and kidney failure. Preclinical studies indicated that vasopressin V(2)-receptor antagonists inhibit cyst growth and slow the decline of kidney function. METHODS: In this phase...

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Autori principali: Torres, Vicente E., Chapman, Arlene B., Devuyst, Olivier, Gansevoort, Ron T., Grantham, Jared J., Higashihara, Eiji, Perrone, Ronald D., Krasa, Holly B., Ouyang, John, Czerwiec, Frank S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3760207/
https://ncbi.nlm.nih.gov/pubmed/23121377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1205511
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