Urine Osmolality, Response to Tolvaptan, and Outcome in Autosomal Dominant Polycystic Kidney Disease: Results from the TEMPO 3:4 Trial

The vasopressin–cAMP–osmolality axis is abnormal in autosomal dominant polycystic kidney disease (ADPKD). In the Tolvaptan Efficacy and Safety in Management of Autosomal Dominant Polycystic Kidney Disease and Its Outcomes 3:4 Trial, a 3-year randomized, placebo-controlled trial in adults, the vasopr...

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Udgivet i:J Am Soc Nephrol
Main Authors: Devuyst, Olivier, Chapman, Arlene B., Gansevoort, Ron T., Higashihara, Eiji, Perrone, Ronald D., Torres, Vicente E., Blais, Jaime D., Zhou, Wen, Ouyang, John, Czerwiec, Frank S.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Nephrology 2017
Fag:
Clinical Epidemiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5407721/
https://ncbi.nlm.nih.gov/pubmed/27920153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2016040448
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