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S(8)-Catalyzed triple cleavage of bromodifluoro compounds for the assembly of N-containing heterocycles

An unprecedented S(8)-catalyzed selective triple-cleavage of bromodifluoroacetamides is disclosed for the first time. Valuable 2-amido substituted benzimidazoles, benzoxazoles and benzothiazoles were obtained in good to excellent yields in a cascade protocol in this strategy. Mechanistic studies sug...

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Bibliografiske detaljer
Udgivet i:Chem Sci
Main Authors: Deng, Shuilin, Chen, Haohua, Ma, Xingxing, Zhou, Yao, Yang, Kai, Lan, Yu, Song, Qiuling
Format: Artigo
Sprog:Inglês
Udgivet: Royal Society of Chemistry 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6657413/
https://ncbi.nlm.nih.gov/pubmed/31391905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9sc01333d
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