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Modeling breast cancer progression to bone: how driver mutation order and metabolism matter

BACKGROUND: Not all the mutations are equally important for the development of metastasis. What about their order? The survival of cancer cells from the primary tumour site to the secondary seeding sites depends on the occurrence of very few driver mutations promoting oncogenic cell behaviours. Usua...

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Detalhes bibliográficos
Publicado no:BMC Med Genomics
Main Authors: Ascolani, Gianluca, Liò, Pietro
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6657267/
https://ncbi.nlm.nih.gov/pubmed/31345216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12920-019-0541-4
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