Single-Dose Tafenoquine to Prevent Relapse of Plasmodium vivax Malaria

BACKGROUND: Treatment of Plasmodium vivax malaria requires the clearing of asexual parasites, but relapse can be prevented only if dormant hypnozoites are cleared from the liver (a treatment termed “radical cure”). Tafenoquine is a single-dose 8-aminoquinoline that has recently been registered for t...

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發表在:N Engl J Med
Main Authors: Lacerda, M.V.G., Llanos-Cuentas, A., Krudsood, S., Lon, C., Saunders, D.L., Mohammed, R., Yilma, D., Batista Pereira, D., Espino, F.E.J., Mia, R.Z., Chuquiyauri, R., Val, F., Casapía, M., Monteiro, W.M., Brito, M.A.M., Costa, M.R.F., Buathong, N., Noedl, H., Diro, E., Getie, S., Wubie, K.M., Abdissa, A., Zeynudin, A., Abebe, C., Tada, M.S., Brand, F., Beck, H.-P., Angus, B., Duparc, S., Kleim, J.-P., Kellam, L.M., Rousell, V.M., Jones, S.W., Hardaker, E., Mohamed, K., Clover, D.D., Fletcher, K., Breton, J.J., Ugwuegbulam, C.O., Green, J.A., Koh, G.C.K.W.
格式: Artigo
語言:Inglês
出版: Massachusetts Medical Society 2019
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6657226/
https://ncbi.nlm.nih.gov/pubmed/30650322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1710775
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