Tafenoquine versus Primaquine to Prevent Relapse of Plasmodium vivax Malaria

BACKGROUND: Tafenoquine, a single-dose therapy for Plasmodium vivax malaria, has been associated with relapse prevention through the clearance of P. vivax parasitemia and hypnozoites, termed “radical cure.” METHODS: We performed a phase 3, prospective, double-blind, double-dummy, randomized, control...

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發表在:N Engl J Med
Main Authors: Llanos-Cuentas, A., Lacerda, M.V.G., Hien, T.T., Vélez, I.D., Namaik-larp, C., Chu, C.S., Villegas, M.F., Val, F., Monteiro, W.M., Brito, M.A.M., Costa, M.R.F., Chuquiyauri, R., Casapía, M., Nguyen, C.H., Aruachan, S., Papwijitsil, R., Nosten, F.H., Bancone, G., Angus, B., Duparc, S., Craig, G., Rousell, V.M., Jones, S.W., Hardaker, E., Clover, D.D., Kendall, L., Mohamed, K., Koh, G.C.K.W., Wilches, V.M., Breton, J.J., Green, J.A.
格式: Artigo
語言:Inglês
出版: Massachusetts Medical Society 2019
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Original Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6657225/
https://ncbi.nlm.nih.gov/pubmed/30650326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1802537
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