Insertion/deletion-activated frame-shift fluorescence protein is a sensitive reporter for genomic DNA editing

BACKGROUND: Reporter methods to quantitatively measure the efficiency and specificity of genome editing tools are important for the development of novel editing techniques and successful applications of available ones. However, the existing methods have major limitations in sensitivity, accuracy, an...

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Dades bibliogràfiques
Publicat a:BMC Genomics
Autors principals: Kumar, Akhilesh, Birnbaum, Michael D., Moorthy, Balaji T., Singh, Jayanti, Palovcak, Anna, Patel, Devang M., Zhang, Fangliang
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2019
Matèries:
Methodology Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6657097/
https://ncbi.nlm.nih.gov/pubmed/31340764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-019-5963-z
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