Insertion/deletion-activated frame-shift fluorescence protein is a sensitive reporter for genomic DNA editing

BACKGROUND: Reporter methods to quantitatively measure the efficiency and specificity of genome editing tools are important for the development of novel editing techniques and successful applications of available ones. However, the existing methods have major limitations in sensitivity, accuracy, an...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:BMC Genomics
Prif Awduron: Kumar, Akhilesh, Birnbaum, Michael D., Moorthy, Balaji T., Singh, Jayanti, Palovcak, Anna, Patel, Devang M., Zhang, Fangliang
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2019
Pynciau:
Methodology Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6657097/
https://ncbi.nlm.nih.gov/pubmed/31340764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-019-5963-z
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