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Insertion/deletion-activated frame-shift fluorescence protein is a sensitive reporter for genomic DNA editing

BACKGROUND: Reporter methods to quantitatively measure the efficiency and specificity of genome editing tools are important for the development of novel editing techniques and successful applications of available ones. However, the existing methods have major limitations in sensitivity, accuracy, an...

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Detalhes bibliográficos
Publicado no:BMC Genomics
Main Authors: Kumar, Akhilesh, Birnbaum, Michael D., Moorthy, Balaji T., Singh, Jayanti, Palovcak, Anna, Patel, Devang M., Zhang, Fangliang
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6657097/
https://ncbi.nlm.nih.gov/pubmed/31340764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-019-5963-z
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