TAF1, associated with intellectual disability in humans, is essential for embryogenesis and regulates neurodevelopmental processes in zebrafish

The TATA-box binding protein associated factor 1 (TAF1) protein is a key unit of the transcription factor II D complex that serves a vital function during transcription initiation. Variants of TAF1 have been associated with neurodevelopmental disorders, but TAF1’s molecular functions remain elusive....

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Veröffentlicht in:Sci Rep
Hauptverfasser: Gudmundsson, Sanna, Wilbe, Maria, Filipek-Górniok, Beata, Molin, Anna-Maja, Ekvall, Sara, Johansson, Josefin, Allalou, Amin, Gylje, Hans, Kalscheuer, Vera M., Ledin, Johan, Annerén, Göran, Bondeson, Marie-Louise
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6656882/
https://ncbi.nlm.nih.gov/pubmed/31341187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-46632-8
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