EOMES interacts with RUNX3 and BRG1 to promote innate memory cell formation through epigenetic reprogramming

Memory CD8(+) T cells have the ability to provide lifelong immunity against pathogens. Although memory features generally arise after challenge with a foreign antigen, naïve CD8 single positive (SP) thymocytes may acquire phenotypic and functional characteristics of memory cells in response to cytok...

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Veröffentlicht in:Nat Commun
Hauptverfasser: Istaces, Nicolas, Splittgerber, Marion, Lima Silva, Viviana, Nguyen, Muriel, Thomas, Séverine, Le, Aurore, Achouri, Younes, Calonne, Emilie, Defrance, Matthieu, Fuks, François, Goriely, Stanislas, Azouz, Abdulkader
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6656725/
https://ncbi.nlm.nih.gov/pubmed/31341159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11233-6
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