Heme oxygenase-1 orchestrates the immunosuppressive program of tumor-associated macrophages

Tumor-associated macrophages (TAMs) contribute to the maintenance of a strong immunosuppressive environment, supporting tumor progression and resistance to treatment. To date, the mechanisms that drive acquisition of these immunosuppressive features are still poorly defined. Heme oxygenase-1 (HO-1)...

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Veröffentlicht in:JCI Insight
Hauptverfasser: Alaluf, Emmanuelle, Vokaer, Benoît, Detavernier, Aurélie, Azouz, Abdulkader, Splittgerber, Marion, Carrette, Alice, Boon, Louis, Libert, Frédérick, Soares, Miguel, Le Moine, Alain, Goriely, Stanislas
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2020
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7308058/
https://ncbi.nlm.nih.gov/pubmed/32369450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.133929
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