Diffusion kurtosis MRI as a predictive biomarker of response to neoadjuvant chemotherapy in high grade serous ovarian cancer

This study assessed the feasibility of using diffusion kurtosis imaging (DKI) as a measure of tissue heterogeneity and proliferation to predict the response of high grade serous ovarian cancer (HGSOC) to neoadjuvant chemotherapy (NACT). Seventeen patients with HGSOC were imaged at 3 T and had biopsy...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Deen, Surrin S., Priest, Andrew N., McLean, Mary A., Gill, Andrew B., Brodie, Cara, Crawford, Robin, Latimer, John, Baldwin, Peter, Earl, Helena M., Parkinson, Christine, Smith, Sarah, Hodgkin, Charlotte, Patterson, Ilse, Addley, Helen, Freeman, Susan, Moyle, Penny, Jimenez-Linan, Mercedes, Graves, Martin J., Sala, Evis, Brenton, James D., Gallagher, Ferdia A.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6656714/
https://ncbi.nlm.nih.gov/pubmed/31341212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-47195-4
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