Phase II Study of Dehydroepiandrosterone in Androgen Receptor‐Positive Metastatic Breast Cancer

LESSONS LEARNED. The androgen receptor (AR) is present in most breast cancers (BC), but its exploitation as a therapeutic target has been limited. This study explored the activity of dehydroepiandrosterone (DHEA), a precursor being transformed into androgens within BC cells, in combination with an a...

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Veröffentlicht in:Oncologist
Hauptverfasser: Pietri, Elisabetta, Massa, Ilaria, Bravaccini, Sara, Ravaioli, Sara, Tumedei, Maria Maddalena, Petracci, Elisabetta, Donati, Caterina, Schirone, Alessio, Piacentini, Federico, Gianni, Lorenzo, Nicolini, Mario, Campadelli, Enrico, Gennari, Alessandra, Saba, Alessandro, Campi, Beatrice, Valmorri, Linda, Andreis, Daniele, Fabbri, Francesco, Amadori, Dino, Rocca, Andrea
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley & Sons, Inc. 2018
Schlagworte:
Clinical Trial Results
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6656524/
https://ncbi.nlm.nih.gov/pubmed/30591548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2018-0243
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