Phase II Study of Dehydroepiandrosterone in Androgen Receptor‐Positive Metastatic Breast Cancer

LESSONS LEARNED. The androgen receptor (AR) is present in most breast cancers (BC), but its exploitation as a therapeutic target has been limited. This study explored the activity of dehydroepiandrosterone (DHEA), a precursor being transformed into androgens within BC cells, in combination with an a...

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Vydáno v:Oncologist
Hlavní autoři: Pietri, Elisabetta, Massa, Ilaria, Bravaccini, Sara, Ravaioli, Sara, Tumedei, Maria Maddalena, Petracci, Elisabetta, Donati, Caterina, Schirone, Alessio, Piacentini, Federico, Gianni, Lorenzo, Nicolini, Mario, Campadelli, Enrico, Gennari, Alessandra, Saba, Alessandro, Campi, Beatrice, Valmorri, Linda, Andreis, Daniele, Fabbri, Francesco, Amadori, Dino, Rocca, Andrea
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley & Sons, Inc. 2018
Témata:
Clinical Trial Results
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6656524/
https://ncbi.nlm.nih.gov/pubmed/30591548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2018-0243
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