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Redesign of a Copper Storage Protein into an Artificial Hydrogenase

We report the construction of an artificial hydrogenase (ArH) by reengineering a Cu storage protein (Cspl) into a Ni-binding protein (NBP) employing rational metalloprotein design. The hypothesis driven design approach involved deleting existing Cu sites of Csp1 and identification of a target tetrat...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:ACS Catal
Hauptverfasser: Selvan, Dhanashree, Prasad, Pallavi, Farquhar, Erik R., Shi, Yelu, Crane, Skyler, Zhang, Yong, Chakraborty, Saumen
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6656401/
https://ncbi.nlm.nih.gov/pubmed/31341700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscatal.9b00360
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