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Silencing of HLA class I on primary human hepatocytes as a novel strategy for reduction in alloreactivity

In contrast to the whole liver, primary hepatocytes are highly immunogenic. Thus, alternative strategies of immunomodulation after hepatocyte transplantation are of special interest. Silencing of HLA class I expression is expected to reduce the strength of allogeneic immune responses and to improve...

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Dettagli Bibliografici
Pubblicato in:J Cell Mol Med
Autori principali: Figueiredo, Constança, Oldhafer, Felix, Wittauer, Eva‐Maria, Carvalho‐Oliveira, Marco, Akhdar, Ali, Beetz, Oliver, Chen‐Wacker, Chen, Yuzefovych, Yuliia, Falk, Christine S., Blasczyk, Rainer, Vondran, Florian W.R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6653539/
https://ncbi.nlm.nih.gov/pubmed/31180181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14484
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