Silencing of HLA class I on primary human hepatocytes as a novel strategy for reduction in alloreactivity

In contrast to the whole liver, primary hepatocytes are highly immunogenic. Thus, alternative strategies of immunomodulation after hepatocyte transplantation are of special interest. Silencing of HLA class I expression is expected to reduce the strength of allogeneic immune responses and to improve...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Figueiredo, Constança, Oldhafer, Felix, Wittauer, Eva‐Maria, Carvalho‐Oliveira, Marco, Akhdar, Ali, Beetz, Oliver, Chen‐Wacker, Chen, Yuzefovych, Yuliia, Falk, Christine S., Blasczyk, Rainer, Vondran, Florian W.R.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6653539/
https://ncbi.nlm.nih.gov/pubmed/31180181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14484
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