Genetic Engineering of the Kidney to Permanently Silence MHC Transcripts During ex vivo Organ Perfusion

Organ gene therapy represents a promising tool to correct diseases or improve graft survival after transplantation. Polymorphic variation of the major histocompatibility complex (MHC) antigens remains a major obstacle to long-term graft survival after transplantation. Previously, we demonstrated tha...

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Dettagli Bibliografici
Pubblicato in:Front Immunol
Autori principali: Yuzefovych, Yuliia, Valdivia, Emilio, Rong, Song, Hack, Franziska, Rother, Tamina, Schmitz, Jessica, Bräsen, Jan Hinrich, Wedekind, Dirk, Moers, Cyril, Wenzel, Nadine, Gueler, Faikah, Blasczyk, Rainer, Figueiredo, Constanca
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7042208/
https://ncbi.nlm.nih.gov/pubmed/32140158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00265
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