Genetic Engineering of the Kidney to Permanently Silence MHC Transcripts During ex vivo Organ Perfusion

Organ gene therapy represents a promising tool to correct diseases or improve graft survival after transplantation. Polymorphic variation of the major histocompatibility complex (MHC) antigens remains a major obstacle to long-term graft survival after transplantation. Previously, we demonstrated tha...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Yuzefovych, Yuliia, Valdivia, Emilio, Rong, Song, Hack, Franziska, Rother, Tamina, Schmitz, Jessica, Bräsen, Jan Hinrich, Wedekind, Dirk, Moers, Cyril, Wenzel, Nadine, Gueler, Faikah, Blasczyk, Rainer, Figueiredo, Constanca
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7042208/
https://ncbi.nlm.nih.gov/pubmed/32140158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00265
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