3D Microfluidic Bone Tumor Microenvironment Comprised of Hydroxyapatite/Fibrin Composite

Bone is one of the most common sites of cancer metastasis, as its fertile microenvironment attracts tumor cells. The unique mechanical properties of bone extracellular matrix (ECM), mainly composed of hydroxyapatite (HA) affect a number of cellular responses in the tumor microenvironment (TME) such...

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Detalhes bibliográficos
Publicado no:Front Bioeng Biotechnol
Main Authors: Ahn, Jungho, Lim, Jungeun, Jusoh, Norhana, Lee, Jungseub, Park, Tae-Eun, Kim, YongTae, Kim, Jangho, Jeon, Noo Li
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Bioengineering and Biotechnology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6653063/
https://ncbi.nlm.nih.gov/pubmed/31380359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2019.00168
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