3D Microfluidic Bone Tumor Microenvironment Comprised of Hydroxyapatite/Fibrin Composite

Bone is one of the most common sites of cancer metastasis, as its fertile microenvironment attracts tumor cells. The unique mechanical properties of bone extracellular matrix (ECM), mainly composed of hydroxyapatite (HA) affect a number of cellular responses in the tumor microenvironment (TME) such...

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Bibliographische Detailangaben
Veröffentlicht in:Front Bioeng Biotechnol
Hauptverfasser: Ahn, Jungho, Lim, Jungeun, Jusoh, Norhana, Lee, Jungseub, Park, Tae-Eun, Kim, YongTae, Kim, Jangho, Jeon, Noo Li
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2019
Schlagworte:
Bioengineering and Biotechnology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6653063/
https://ncbi.nlm.nih.gov/pubmed/31380359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2019.00168
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