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Microfluidic Device for Recreating a Tumor Microenvironment in Vitro

We have developed a microfluidic device that mimics the delivery and systemic clearance of drugs to heterogeneous three-dimensional tumor tissues in vitro. Nutrients delivered by vasculature fail to reach all parts of tumors, giving rise to heterogeneous microenvironments consisting of viable, quies...

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Détails bibliographiques
Auteurs principaux: Toley, Bhushan J., Ganz, Dan E., Walsh, Colin L., Forbes, Neil S.
Format: Artigo
Langue:Inglês
Publié: MyJove Corporation 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3308576/
https://ncbi.nlm.nih.gov/pubmed/22126742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/2425
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