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Ethyl pyruvate attenuates ventilation‐induced diaphragm dysfunction through high‐mobility group box‐1 in a murine endotoxaemia model

Mechanical ventilation (MV) can save the lives of patients with sepsis. However, MV in both animal and human studies has resulted in ventilator‐induced diaphragm dysfunction (VIDD). Sepsis may promote skeletal muscle atrophy in critically ill patients. Elevated high‐mobility group box‐1 (HMGB1) leve...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Liu, Yung‐Yang, Chen, Ning‐Hung, Chang, Chih‐Hao, Lin, Shih‐Wei, Kao, Kuo‐Chin, Hu, Han‐Chung, Chang, Gwo‐Jyh, Li, Li‐Fu
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6652995/
https://ncbi.nlm.nih.gov/pubmed/31339670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14478
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