Ethyl pyruvate attenuates ventilation‐induced diaphragm dysfunction through high‐mobility group box‐1 in a murine endotoxaemia model

Mechanical ventilation (MV) can save the lives of patients with sepsis. However, MV in both animal and human studies has resulted in ventilator‐induced diaphragm dysfunction (VIDD). Sepsis may promote skeletal muscle atrophy in critically ill patients. Elevated high‐mobility group box‐1 (HMGB1) leve...

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Veröffentlicht in:J Cell Mol Med
Hauptverfasser: Liu, Yung‐Yang, Chen, Ning‐Hung, Chang, Chih‐Hao, Lin, Shih‐Wei, Kao, Kuo‐Chin, Hu, Han‐Chung, Chang, Gwo‐Jyh, Li, Li‐Fu
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2019
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6652995/
https://ncbi.nlm.nih.gov/pubmed/31339670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14478
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