Aggregatibacter actinomycetemcomitans Leukotoxin (LtxA) Requires Death Receptor Fas, in Addition to LFA-1, To Trigger Cell Death in T Lymphocytes

Leukotoxin (LtxA) (trade name, Leukothera) is a protein secreted by the oral bacterium Aggregatibacter actinomycetemcomitans. A. actinomycetemcomitans is an oral pathogen strongly associated with development of localized aggressive periodontitis. LtxA acts as a virulence factor for A. actinomycetemc...

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Vydáno v:Infect Immun
Hlavní autoři: Vega, Brian A., Schober, Liam T., Kim, Tami, Belinka, Benjamin A., Kachlany, Scott C.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2019
Témata:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6652782/
https://ncbi.nlm.nih.gov/pubmed/31109948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00309-19
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