Effect of Filgotinib vs Placebo on Clinical Response in Patients With Moderate to Severe Rheumatoid Arthritis Refractory to Disease-Modifying Antirheumatic Drug Therapy: The FINCH 2 Randomized Clinical Trial

IMPORTANCE: Patients with active rheumatoid arthritis (RA) despite treatment with biologic disease-modifying antirheumatic drug (bDMARD) therapy need treatment options. OBJECTIVE: To evaluate the effects of filgotinib vs placebo on the signs and symptoms of RA in a treatment-refractory population. D...

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Bibliografski detalji
Izdano u:JAMA
Glavni autori: Genovese, Mark C., Kalunian, Kenneth, Gottenberg, Jacques-Eric, Mozaffarian, Neelufar, Bartok, Beatrix, Matzkies, Franziska, Gao, Jie, Guo, Ying, Tasset, Chantal, Sundy, John S., de Vlam, Kurt, Walker, David, Takeuchi, Tsutomu
Format: Artigo
Jezik:Inglês
Izdano: American Medical Association 2019
Teme:
Original Investigation
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6652745/
https://ncbi.nlm.nih.gov/pubmed/31334793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jama.2019.9055
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