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Bryostatin‐1 ameliorated experimental colitis in Il‐10 (−/−) Mice by protecting the intestinal barrier and limiting immune dysfunction

Bryostatin‐1 (Bry‐1) has been proven to be effective and safe in clinical trials of a variety of immune‐related diseases. However, little is known about its effect on Crohn's disease (CD). We aimed to investigate the impact of Bry‐1 on CD‐like colitis and determine the mechanism underlying this...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Zuo, Lugen, Li, Jing, Ge, Sitang, Ge, Yuanyuan, Shen, Mengdi, Wang, Yan, Zhou, Changmin, Wu, Rong, Hu, Jianguo
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6652299/
https://ncbi.nlm.nih.gov/pubmed/31251471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14457
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