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The formation of giant plasma membrane vesicles enable new insights into the regulation of cholesterol efflux

Aberrant cellular cholesterol accumulation contributes to the pathophysiology of many diseases including neurodegenerative disorders such as Niemann-Pick Type C (NPC) and Alzheimer’s Disease(1–4). Many aspects of cholesterol efflux from cells remain elusive. Here we describe the utility of cholester...

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Detalles Bibliográficos
Publicado en:Exp Cell Res
Main Authors: Sedgwick, Alanna, Balmert, M. Olivia, D’Souza-Schorey, Crislyn
Formato: Artigo
Idioma:Inglês
Publicado: 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6652231/
https://ncbi.nlm.nih.gov/pubmed/29522754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2018.03.001
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