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Extracellular microvesicles and invadopodia mediate non-overlapping modes of tumor cell invasion

Tumor cell invasion requires the molecular and physical adaptation of both the cell and its microenvironment. Here we show that tumor cells are able to switch between the use of microvesicles and invadopodia to facilitate invasion through the extracellular matrix. Invadopodia formation accompanies t...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Sedgwick, Alanna E., Clancy, James W., Olivia Balmert, M., D’Souza-Schorey, Crislyn
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4602187/
https://ncbi.nlm.nih.gov/pubmed/26458510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep14748
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