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Extracellular microvesicles and invadopodia mediate non-overlapping modes of tumor cell invasion

Tumor cell invasion requires the molecular and physical adaptation of both the cell and its microenvironment. Here we show that tumor cells are able to switch between the use of microvesicles and invadopodia to facilitate invasion through the extracellular matrix. Invadopodia formation accompanies t...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Sedgwick, Alanna E., Clancy, James W., Olivia Balmert, M., D’Souza-Schorey, Crislyn
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4602187/
https://ncbi.nlm.nih.gov/pubmed/26458510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep14748
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