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Epigenetic Reprogramming and Emerging Epigenetic Therapies in CML

Chronic myeloid leukemia (CML) is a hematopoietic stem cell disorder characterized by BCR-ABL1, an oncogenic fusion gene arising from the Philadelphia chromosome. The development of tyrosine kinase inhibitors (TKIs) to overcome the constitutive tyrosine kinase activity of the BCR-ABL protein has dra...

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Bibliografische gegevens
Gepubliceerd in:Front Cell Dev Biol
Hoofdauteurs: Bugler, Jane, Kinstrie, Ross, Scott, Mary T., Vetrie, David
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2019
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6652210/
https://ncbi.nlm.nih.gov/pubmed/31380371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2019.00136
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