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Epigenetic Reprogramming and Emerging Epigenetic Therapies in CML
Chronic myeloid leukemia (CML) is a hematopoietic stem cell disorder characterized by BCR-ABL1, an oncogenic fusion gene arising from the Philadelphia chromosome. The development of tyrosine kinase inhibitors (TKIs) to overcome the constitutive tyrosine kinase activity of the BCR-ABL protein has dra...
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| Publicado no: | Front Cell Dev Biol |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6652210/ https://ncbi.nlm.nih.gov/pubmed/31380371 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2019.00136 |
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