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Metformin reverses mesenchymal phenotype of primary breast cancer cells through STAT3/NF-κB pathways

BACKGROUND: Breast cancer currently is the most frequently diagnosed neoplasm and the leading cause of death from cancer in women worldwide, which is mainly due to metastatic disease. Increasing our understanding of the molecular mechanisms leading to metastasis might thus improve the pharmacologica...

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Bibliografski detalji
Izdano u:BMC Cancer
Glavni autori: Esparza-López, José, Alvarado-Muñoz, Juan Francisco, Escobar-Arriaga, Elizabeth, Ulloa-Aguirre, Alfredo, de Jesús Ibarra-Sánchez, María
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6651945/
https://ncbi.nlm.nih.gov/pubmed/31337349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-019-5945-1
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