NIRF-Molecular Imaging with Synovial Macrophages-Targeting Vsig4 Nanobody for Disease Monitoring in a Mouse Model of Arthritis

Nanobody against V-set and Ig domain-containing 4 (Vsig4) on tissue macrophages, such as synovial macrophages, could visualize joint inflammation in multiple experimental arthritis models via single-photon emission computed tomography imaging. Here, we further addressed the specificity and assessed...

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Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Zheng, Fang, Luo, Siyu, Ouyang, Zhenlin, Zhou, Jinhong, Mo, Huanye, Schoonooghe, Steve, Muyldermans, Serge, De Baetselier, Patrick, Raes, Geert, Wen, Yurong
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6651725/
https://ncbi.nlm.nih.gov/pubmed/31288389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20133347
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