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Insulin Treatment Forces Arteriogenesis in Diabetes Mellitus by Upregulation of the Early Growth Response-1 (Egr-1) Pathway in Mice

The process of arteriogenesis is severely compromised in patients with diabetes mellitus (DM). Earlier studies have reported the importance of Egr-1 in promoting collateral outward remodeling. However, the role of Egr-1 in the presence of DM in outward vessel remodeling was not studied. We hypothesi...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Thulasingam, Senthilkumar, Krishnasamy, Sundar, Raj C., David, Lasch, Manuel, Vedantham, Srinivasan, Deindl, Elisabeth
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6651530/
https://ncbi.nlm.nih.gov/pubmed/31284541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20133320
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