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Development of Novel antimiRzymes for Targeted Inhibition of miR-21 Expression in Solid Cancer Cells

MicroRNAs (miRNAs) are short non-coding RNAs that are involved in the regulation of gene expression. Previous reports showed an over-expression of miRNA-21 (miR-21) in various cancer cells, and its up-regulation is closely related to cancer initiation, proliferation and metastasis. In this work, we...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Larcher, Leon M., Wang, Tao, Veedu, Rakesh N.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6651226/
https://ncbi.nlm.nih.gov/pubmed/31284665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24132489
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