Neuromodulatory Action of Picomolar Extracellular Aβ42 Oligomers on Presynaptic and Postsynaptic Mechanisms Underlying Synaptic Function and Memory

Failure of anti-amyloid-β peptide (Aβ) therapies against Alzheimer's disease (AD), a neurodegenerative disorder characterized by high amounts of the peptide in the brain, raised the question of the physiological role of Aβ released at low concentrations in the healthy brain. To address this que...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Gulisano, Walter, Melone, Marcello, Ripoli, Cristian, Tropea, Maria Rosaria, Li Puma, Domenica D., Giunta, Salvatore, Cocco, Sara, Marcotulli, Daniele, Origlia, Nicola, Palmeri, Agostino, Arancio, Ottavio, Conti, Fiorenzo, Grassi, Claudio, Puzzo, Daniela
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2019
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6650983/
https://ncbi.nlm.nih.gov/pubmed/31127002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0163-19.2019
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