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The Significance of IL-36 Hyperactivation and IL-36R Targeting in Psoriasis
Psoriasis is an immune-mediated inflammatory skin disease that involves mainly T helper (Th)17, Th1 and Th22 lymphocytes, which cause hyper-proliferation of the epidermis with aberrant differentiation of keratinocytes, and local production of chemokines and cytokines. These fuel a self-amplifying lo...
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| Veröffentlicht in: | Int J Mol Sci |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
MDPI
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6650959/ https://ncbi.nlm.nih.gov/pubmed/31284527 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20133318 |
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